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Several mechanisms may potentially contribute to blood pressure effects, including: weight loss (a well-established factor in blood pressure reduction), possible promotion of natriuresis (sodium excretion by the kidneys), and theoretical improvements in endothelial functionthough many of these mechanisms remain hypothetical rather than definitively proven
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Hospital inpatients typically receive variable rate intravenous insulin infusions during major surgery, transitioning to subcutaneous insulin regimens post-operatively until oral intake resumes and Mounjaro can be safely restarted, as outlined in CPOC guidance

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