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Both the STEP-1 and SURMOUNT-4 trials included the availability of RDN dietary counseling and recommendations to exercise 150 min/week during the treatment period, but with notable weight regain for most participants upon GLP-1 discontinuation without continued nutrition support [18,273]

as well as the hippocampus

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[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Ma RL, Deng Y, Wang YF, Zhu SY, Ding XS, Sun AJ

Role of CCAAT enhancer-binding protein beta in the thyroid hormone and cAMP induction of phosphoenolpyruvate carboxykinase gene transcription

However, plasma levels of GIP remained unchanged between the two groups