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In APP/PS1 transgenic mice, (D-Ser2)Oxm, a dual GLP-1 and Gcg receptor agonist, notably improves spatial memory and synaptic plasticity, reduces A plaque deposition in the hippocampus, and modulates the PI3K/AKT1/GSK3 signaling pathway [84]

Ejercicio y sensibilidad a la insulina La actividad fsica de intensidad moderada, como caminar a paso ligero, montar en bicicleta o hacer ejercicios de fuerza, aumenta la secrecin de GLP-1

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16%, respectively)

Brown adipocyte-specific NKO (BANKO) mice were also established, and their metabolic phenotypes were directly compared with that of ANKO mice

2020;105:e2695e2709