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[DOI] [PubMed] [Google Scholar] 29.Gere-Paszti E, Jakus J

The mechanisms underlying muscle preservation likely involve tesofensine's enhancement of dopaminergic and noradrenergic signaling, which may support protein synthesis pathways and reduce muscle atrophy signaling

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Kashou AH, Agarwal A (2011) Oxidants and antioxidants in the pathogenesis of HIV/AIDS

In an additional embodiment the formulations or compositions described herein provide a therapeutically effective amount of at least one active pharmaceutical ingredient at the site of disease with no detectable systemic exposure