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Front Biosci

doi: 10.1001/jamanetworkopen.2020.36227

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The disease can cause severe defoliation, which can start as early as August

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However, a negative finding by FISH will not necessarily rule out malignancy, and to date, we still need good clinicopathologic correlation as well as long-term follow-up to completely rule out malignant behavior in the majority of borderline lesions
