does semaglutide cause stomach bloating The GLP-1 Bulge: Is a Normal Side Effect? Bloating from GLP-1 Injections -
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That said, there are temperature extremes that can degrade the drugs effectiveness, especially if it freezes

Be aware of warning signs that require immediate medical attention: severe abdominal pain (possibly radiating to the back), persistent vomiting, yellowing of skin or eyes, or signs of allergic reaction

Cell Metab 29 , 837843 (2019)
Avoid leaving the vial in your car or other areas where it might freeze during winter

For many patients, compounded injections offer reliable appetite control and metabolic benefits

Because alcohol is calorie-dense, semaglutide's appetite-suppressing properties may broadly diminish the drive to consume liquid calories, though the current study could not determine if the reduction in drinking occurs independently of weight loss
