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Finally, we reported causal effects indicating that the role of GLP-1 RAs in reducing the risk of depression and emotional instability may be mediated by BMI reduction, as shown in Figure 8

In individuals with T2DM, these agents can be used throughout the course of the disease

Shortages occurred as demand outpaced supply from traditional pharmaceutical manufacturers

The active ingredient in Mounjaro (tirzepatide) has also been associated with significant weight loss

However, GLP-1 users exhibited a marginally elevated risk for kidney cancer, according to investigators

Obesity and overweight [internet]
