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P=0.001] and whole-body bone mineral density [MD0.02 kg/m2 (95% CI,0.04 to0.00)

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Although long-term safety and efficacy require further evaluation, current evidence positions GLP-1 RAs as promising therapeutic agents in translational geroscience, with the potential to mitigate age-related physiological decline and promote a longer, healthier lifespan.

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