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Our findings align with emerging case reports and pharmacovigilance signals suggesting vestibular effects of GLP-1RAs

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Individuals with certain allele combinations may experience more pronounced thermoregulatory effects when taking semaglutide, even at the same dose as someone with different genetic markers

36,37,38 Therefore, the weight loss results reported here are likely to underestimate the effect of the newer, more potent GLP-1 RAs semaglutide and tirzepatide