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These benefits were achieved without serious adverse effects, and GLP-1 RA use was associated with reduced reliance on acetazolamide and avoidance of surgical interventions

Published online January 2, 2026:10600280251407145

doi: 10.1172/JCI186652 47 GuarnottaVBiancoMJVigneriEPantoFLo SassoBCiaccioMet al

You developed serious side effects such as gastroparesis, pancreatitis, or intestinal blockage

Cosmos Study October 10, 2023 Dual-Team Study Team A:Kersten Bartelt, RNBrendan Joyce Team B:Matthew Gracianette, MDEvan Bryer Key Findings The rate of thyroid cancer for type 2 diabetic patients prescribed semaglutide or dulaglutide is lower than the rate for patients prescribed insulin

Many practitioners recommend supplementing with oral methylcobalamin or sublingual B12 in addition to the compound, particularly for patients who have been on therapy for more than six months or who have documented low B12 levels