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The reason they require injection rather than oral administration is straightforward biochemistry: the gastrointestinal tract degrades most therapeutic peptides before they can reach systemic circulation

This will push penetration well beyond the wealthy self-payer segment that has driven adoption so far: Of the 2.4 million British GLP-1 users in 2024, only 220,000 were doing so through the National Health Service (NHS)

Patients with diabetes or at risk of diabetes require particularly close glucose monitoring due to corticosteroids' hyperglycaemic effects

Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist authorised in the UK for type 2 diabetes and weight management

Uncertain Dosage Accuracy Accurate dosing is crucial for semaglutide

I'll link to it so you know exactly what labs I'm talking about and what those markers should be