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These results provide new insights into the molecular basis of ligand specificity in class B GPCRs and may facilitate the development of more specific therapeutics.

With the highest 12 mg dose of retatrutide (Eli Lilly) an investigational #GLP1, glucose-dependent insulinotropic polypeptide (GIP) and glucagon receptor agonist nearly two-thirds of participants lost 20% or more of their body weight, half of participants lost 25% of their body weight and one-quarter of participants lost more than 30% of their body weight

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These findings are revolutionary, and they offer hope for individuals struggling with obesity or difficulty losing weight through traditional methods alone

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