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However, the HSE advises that a healthy diet and regular exercise are the most effective way to lose weight and improve your health in the long-term

The SURMOUNT-1 trial recorded 22.5% average weight loss at this dose, roughly 52 pounds

Given the early stage of the evidence base, with only one randomized controlled trial and several heterogeneous nonrandomized studies, the review was designed a priori as a qualitative synthesis rather than a quantitative metaanalysis

Maximum eligibility across every pathway

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Sci China Life Sci 61:373379