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10.1146/annurev-physiol-031522-021457 27 KuhnV.DiederichL.KellerT

Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes

Proc Natl Acad Sci USA 1995

LSDs, whose common pathophysiological aspects include lysosomal dysfunction due to the loss of function of lysosomal enzymes, provide good examples of diverse therapeutic strategies aimed at restoring lysosomal function downstream of different defects

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