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NICE has recommended Wegovy (semaglutide) for reducing the risk of major adverse cardiovascular events in patients with existing cardiovascular disease who are overweight or obese

Should I get genetic testing to personalize my semaglutide therapy

When combining the two, expect nausea to be most pronounced during dose escalation periods, particularly when both compounds are being increased in close succession

Inflammatory cytokine expression by real-time PCR To confirm the results obtained from the antibody array membrane and ELISA at the level of mRNA expression, real-time PCR was performed on mouse CSMCs treated with vehicle, LPS (1 g/mL), LPS (1 g/mL)+exendin-4 (50 nM), or LPS (1 g/mL)+exendin-4 (100 nM)

doi: 10.1056/NEJMoa2107519

GIP-1 has an anti-inflammatory effect, though GIP-1 level was reduced in obese and T2DM patients