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The primary advantage is improved convenience and potentially better adherence, as patients only need to remember one injection per week

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The mean change in HbA1c was not different between the two approaches (WMD 0.08%, 95% CI 1.07 to 1.23)

Patients with prior exposure to either drug class, a recent dementia diagnosis, or recent hospitalisation were excluded

Furthermore, Pendulum has taken the step of funding or sponsoring clinical trials of its products, in which participants saw such improvements as lower hemoglobin A1c and reduced fatigue and bloating.27 28 Notwithstanding the potential bias that self-conducted studies may have, these trials give us insight into Pendulums efficacy that other brands have not provided, and which may not have come to light without Pendulums funding

Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet