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[17] [18] However, acid reflux or heartburn is not consistently reported as a distinct adverse event category in pivotal trials

In conclusion, GLP-1 and its analogues have an important immunomodulatory effect in innate like lymphocytes

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Central administration of GLP-1RAs reduces food intake, likely via GLP-1 receptorexpressing regions in the hypothalamus and brainstem (Kastin and Akerstrom, 2003), many of which are also estrogen targets (Kanoski et al., 2011), supporting a potential interaction between these systems (Miller, 2012)

The patch format also makes it appealing for people who prefer not to take tablets or drinks multiple times a day

10.1056/NEJMoa1616011 [DOI] [PubMed] [Google Scholar] 95