how do glp-1 drugs work for weight loss Agonists: Using Semaglutide, Tirzepatide, and Orforglipron and Obesity GLP-1 Drugs for Weight Loss
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In direct comparison trials for diabetes (SURPASS-2 compared tirzepatide to semaglutide 1 mg), tirzepatide showed superior blood sugar control and greater weight loss

Nauck M, Frid A, Hermansen K, Shah NS, Tankova T, Mitha IH, et al

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Safety and discontinuation rates are comparable to other GLP-1 drugs

Heiss, C
Hansen HH, Fabricius K, Barkholt P, Niehoff ML, Morley JE, Jelsing J, et al
