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KBs and KD as Epigenetic and Post-Translational Modifiers of Histones and Non-Histone Proteins SIRT1 is associated with the health and longevity effects of CR and mediates the neurological benefits of a KD [26]

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations apoE: apolipoprotein E CBS: cystathionine -synthase GADD153: growth arrest- and DNA damage-inducible gene 153 HHcy: hyperhomocysteinemia eIF2 : eukaryotic initiation factor-2 ER: endoplasmic reticulum GRP: glucose-regulated protein MCP-1: monocyte chemoattractant protein 1 MTHFR: 5,10-methylene tetrahydrafolate reductase PERK: PKR-like ER kinase ROS: reactive oxygen species TDAG51: T-cell death-associated gene 51 UPR: unfolded protein response XBP-1: X-box binding protein-1 References Ross R (1999) Atherosclerosis an inflammatory disease

However, a reduction in the minimum inhibitory concentrations of antibiotics by its use could make it a beneficial auxiliary compound for treatment of severe or recalcitrant bacterial infections of the upper respiratory tract

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