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A 2026 BMJ review estimated full weight regain within about 1.7 years

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Depending on the dose and indication, up to 70% of patients may experience some GI effects, with higher rates typically seen at weight management doses (2.4 mg) and during dose escalation

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JAMA 298:194206 Phung OJ, Scholle JM, Talwar M, Coleman CI (2010) Effect of noninsulin antidiabetic drugs added to metformin therapy on glycemic control, weight gain, and hypoglycemia in type 2 diabetes

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