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Exenatide once weekly decreases urinary albumin excretion in patients with type 2 diabetes and elevated albuminuria: Pooled analysis of randomized active controlled clinical trials

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( K ) DPP4 activity, ( L ) soluble DPP4 concentration, ( M ) active GLP-1, ( N ) active GIP, ( O ) insulin, and ( P ) glucagon from the PV and CP 15 minutes after glucose bolus in Dpp4 EC+/+ ( n = 713) and Dpp4 EC/ ( n = 611) mice

Sodium monoiodoacetate (MIA) model of OA in mice Animal handling was performed according to the guidelines of the Federation of European Laboratory Animal Science Associations (FELASA)

Some researchers have proposed that chronic inflammation, insulin resistance, and metabolic dysfunction contribute directly to these structural changes