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SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function

These omics-based biomarkers are promising for future clinical stratification, but require validation and standardization before widespread adoption [130,137]

2021 May 6;384(18):171930

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For type 2 diabetes , NICE recommends GLP-1 receptor agonists as second- or third-line therapy when metformin and other oral agents have not achieved adequate glycaemic control, or as an alternative to insulin in certain circumstances