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Thromb Res 75:383394

Comparing tirzepatide and semaglutide Mechanism of action Semaglutide is a long-acting GLP-1 receptor agonist that stimulates glucose-dependent insulin secretion, suppresses glucagon release, delays gastric emptying and induces satiety

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Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes

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Dose timing, titration speed, or other health factors may need consideration