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The chamber of Vitrobot was set to 100% humidity at 4 C

Nausea is one of the most frequently reported side effects associated with retatrutide in clinical trials to date, as documented in the Phase 2 randomised controlled trial published in the New England Journal of Medicine in June 2023 (Jastreboff et al., NEJM 2023)

Most studies show the full effect over 6-12 months of consistent use

Studies have demonstrated Semaglutides effectiveness in significant weight reduction

For clinicians, GLP-1 RAs may be a pragmatic consideration in HS management where weight loss is a goal and comorbid metabolic risk is present, pending confirmatory evidence