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These viruses are injected into the tumour or peritumoural region, and because viruses are self-replicating, multi dosing is not a limitation (figure 2B)

Important safety considerations include the boxed warning for thyroid C-cell tumors (contraindicated in patients with personal/family history of MTC or MEN2), and risks of pancreatitis, gallbladder problems, diabetic retinopathy complications, and acute kidney injury from dehydration
[DOI] [PubMed] [Google Scholar] 86.Thomas C, Auwerx J & Schoonjans K Bile acids and the membrane bile acid receptor TGR5-connecting nutrition and metabolism
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To view a copy of this licence, visit About this article Cite this article Suter, B., Rhodes, A., Bigeh, A
