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You can read the full article at The worldwide obesity epidemic is accompanied by a higher incidence of cardiovascular disease (CVD), specifically stroke and heart attacks

How does this apply if I am also taking berberine or other supplements

Blood pressure actually improved in most participants, a benefit attributed to weight loss and improved insulin sensitivity outweighing any direct cardiovascular stimulation from the drug itself

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This is why medical teams keep a close eye on how patients are doing as they adjust doses

The brand names of metformin include Glucophage, Riomet, and Glumetza