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Consequently, GLP1R has been a target for developing drugs usually referred to as GLP1R agonists to treat diabetes
126,128 ) on metabolic side effects (for example, hyperglycemia, hyperlipidaemia, weight gain) of atypical antipsychotics including olanzapine, quetiapine, brexpiprazole and clozapine

The risk is generally highest during the initial weeks of treatment and following dose increases, with symptoms often improving as the body adjusts to the medication

Their use was associated with reduced mortality and improved cardiovascular and kidney outcomes in matched control studies

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