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Clinical studies have demonstrated significant reductions in hemoglobin A1c (averaging 1.92.4% depending on dose) and substantial weight loss (averaging 1521% of body weight in obesity trials at the highest doses)

It has been shown using various atherosclerosis animal models that GLP-1RA therapy is associated with a reduction in atherosclerotic plaques, prevention of aorta intima-media thickening, improvement in vascular endothelial function, reduction of the necrotic zone and an increase of the fibrous component in the plaque and plaque stabilisation

If youre considering GLP-1 treatment during perimenopause or menopause, discuss your full health picture with your healthcare provider, including any HRT youre taking and your approach to nutrition and exercise

Examples include permanent vision loss, severe gastroparesis requiring feeding tubes, or kidney failure requiring dialysis

Available online: 11.Kleinman N., Abouzaid S., Andersen L., Wang Z., Powers A