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Spectral-domain OCT

confirmed and extended the observation, where GLP-1 significantly increased myocardial glucose uptake under basal conditions in lean humans, but this effect was impaired in T2D [47]

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Pathogenesis of Diabetic Gastroparesis There are multiple mechanisms linking diabetes to gastric motor dysfunction, such as autonomic neuropathy, enteric neuropathy involving excitatory and inhibitory nerves, abnormalities of ICC [54] (Table 3), acute fluctuations in blood glucose, incretin-based medications used to normalize postprandial blood glucose (Table 5) and perhaps psychosomatic factors via autonomic mechanisms