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A new study suggests that the effectiveness of widely used GLP-1 weight-loss drugs may depend strongly on consistent use.

For context, tirzepatide 15 mg was associated wtih 22.5% average weight loss at 72 weeks

Are the problems a coincidence or related to the drug?

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To date, the protective cardiovascular effects of these drugs in patients with and without T2D are not completely understood and several mechanisms have been proposed
