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Many patients describe this as a persistent Wegovy taste in mouth, especially after meals or during early treatment phases

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For example, nausea affects approximately 44% of patients taking Saxenda, 43.9% with Wegovy at the maintenance dose, and 24-40% with Mounjaro depending on dose

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Half of the group was given tirzepatide over the course of 52 weeks, the other half was given a placebo

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The median follow-up was only 47 days, too short for most patients to lose enough weight to meaningfully alter their levothyroxine requirements through the weight-based mechanism alone

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Updated January 13, 2026

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Lin HT, et al

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