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This disruptor increased SOD-like activity (increasing the concentration of hydrogen peroxide) and suppressed catalase-like activity, enhancing the overall cellular level of hydrogen peroxide and supporting the efficacy of chemodynamic therapy
On the other hand, exosomes from cells with reparative potential, such as bone marrow mesenchymal stem cells (MSCs) or amniotic epithelial cells, have been found to downregulate the pro-ferroptotic lipid metabolism enzyme ACSL4, or upregulate parallel anti-ferroptosis pathways like FSP1/GPX4, thereby attenuating ferroptosis and promoting cartilage repair (Wang Y
doi: 10.1007/s11940-010-0090-9
Nevertheless, cancer cells may employ the NRF2 transcription factor to counteract the excessive production of ROS [70]
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals
Fisetin and its role in chronic diseases
