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This dual action helps regulate appetite, increase feelings of fullness, improve insulin sensitivity, and ultimately support significant weight loss

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Dual pathway activation provides complementary appetite suppression through amylin and GLP-1 receptors simultaneously

It was first characterized by Predrag Sikiric and colleagues at the University of Zagreb in the early 1990s, and a 2025 literature and patent review cataloged its effects across gastrointestinal, musculoskeletal, and neural models

[DOI] [PubMed] [Google Scholar] 31 .Sviri S, Khalaila R, Daher S, et al

Choline Metabolizes fats in the liver and gall bladder