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In simpler terms, GLP-1 RAs might have beneficial effects on the metabolic health of peripheral organs (such as the liver and muscles) by enhancing insulin sensitivity, decreasing fat accumulation, and promoting muscle mass, which can help mitigate sarcopenia, a common age-related condition

The primary cause of obesity is excessive food intake

Resources on muscle loss during GLP-1 therapy provide additional context for those concerned about this issue

3.1 SGLT2i and AMPK The SGLT2i (Sodium-glucose co-transport 2 inhibitors) are a class of antidiabetic agents, targeting the major glucose transporter SGLT2 in the kidney

Treat it as promising, not established