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GLP-1 RAs offer improved glycaemia, weight loss and cardiovascular benefits in those for whom they are recommended by the guidelines, so it is important that we facilitate their initiation and continuation in as many appropriate people as possible

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Retatrutides Phase 2 data also demonstrated robust improvements in blood pressure, fasting glucose, and triglycerides

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Since it is often the case that the efficacious acute-phase treatment is continued into the maintenance phase, clinicians need to factor in this possibility when deciding to initiate OFC for bipolar depression

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