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By forming a gel-like matrix in the digestive tract, it slows gastric emptying and the absorption of carbohydrates, which contributes to a more balanced glycemic curve and extended satiety

[DOI] [PMC free article] [PubMed] [Google Scholar] 501.Irie S., Matsumura Y., Zdravkovic M., Jacobsen L.V., Kageyama S

Fueled by the FDAs approval of Wegovy for weight loss in 2021, prescriptions for GLP-1 (glucagon-like peptide-1) drugs rose 587% from 2019 to 2024 as usage expanded beyond diabetes management

Evidence has recently revealed that GLP-1RAs inhibit cardiac hypertrophy by upregulating GLP-1R expression and activating the AMPK/mechanistic target of the rapamycin (mTOR) signaling pathway [78]

[DOI] [PMC free article] [PubMed] [Google Scholar] 179.Chen D, Liao J, Zhou C, et al

Receptors and effects of gut hormones in three osteoblastic cell lines