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Animal models of abuse and addiction tend to focus on the ability of the drugs to directly control the animals behavior and to induce a rewarding effect that is not dependent on preexisting conditions [161]

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Seeking ongoing support, staying engaged in healthy activities, and focusing on the benefits of a smoke-free life can all contribute to long-term success

These factors can lead to tooth loss, which progresses to jawbone loss

In a field often polarized between alarmism and uncritical endorsement, this Review advocates for something more rigorous: evidence-led evaluation grounded in long-term data
