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Smoking is responsible for approximately half of all bladder cancer cases in both men and women, with current smokers facing up to a fourfold higher risk compared to those who have never smoked

The pleasurable effects lead to repeated use which in turn activates the brains reward system

[DOI] [PMC free article] [PubMed] [Google Scholar] ISO Biological Evaluation of Medical Devices-Part 5: Tests for in Vitro Cytotoxicity

Popular with adults who prefer a cigarette-style hand-to-mouth ritual, they offer the familiar experience without tobacco or nicotine

[2] Smoking rates are almost twice as high in those with substance use disorders compared to the general population, which may be a result of the shared neurobiological pathways between addictive substances

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