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The GIP component adds: Enhanced Insulin Response: Even stronger blood sugar control than GLP-1 alone Better insulin secretion timing Improved insulin sensitivity in tissues Fat Metabolism Effects: GIP receptors exist in fat tissue May influence how body stores and uses fat Potentially increases fat burning Synergistic Appetite Suppression: GIP and GLP-1 together produce greater appetite reduction More potent satiety signals Stronger overall effect This explains why tirzepatide produces 5-7% more weight loss than semaglutidethe dual action is more powerful than GLP-1 alone

[DOI] [PubMed] [Google Scholar] 3.Peeters A., Barendregt J.J., Willekens F., Mackenbach J.P., Mamun A.A., Bonneux L

Foods that one person tolerates may cause issues for another

For example, the STEP 1 trial of once-weekly semaglutide (2.4 mg) in people without diabetes achieved a ~15% average body weight reduction over 68 weeks (source), with a mean baseline BMI of ~38 (source)

Your specific treatment plan includes the type of GLP-1 medication you need, the dose, and your injection schedule

Since many people eat less overall on GLP-1 medications, each meal and snack matters more