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4G, H), suggesting that acute hypoxia can indeed influence the glyoxalase system, namely through downregulation of GLO2

According to Allen and Tresini (12), almost half of the ROS effects reported involve members of the mitogen-activated protein kinase (MAP kinase) and nuclear factor -B (NF B) pathways, but effects are not limited to these processes

Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF--dependent IL-6 secretion in normal human dermal fibroblasts

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Using the same principle, the group leveraged flow chemistry to build covalent protein dimers directly in the solid support using Lys as a bifunctional handle 67