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The activation and/or upregulation of many xenobiotic metabolism enzymes is driven by exposure to chemicals that can serve as substrates

Another concern with these products are the high concentrations of nicotine, which may contribute to addiction, especially for youth who are experimenting with the products

Crafted with robust materials, the water and windproof lighter combines functionality and style, making it a versatile choice for both personal and professional settings

PMID 26085122

Traditionally, blunts were made with a tobacco wrap though increased restrictions and regulations on tobacco and nicotine products in the cannabis industry have prevented cannabis companies from being able to use tobacco wraps with blunts on the shelf