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Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity

Liraglutide has a longer track record and more long-term data on outcomes, though it requires a daily injection

347 MiR-181a increases the abundance of beneficial bacteria, inhibits the expression of the inflammatory cytokines IL-6, TNF- and IL-1, upregulates the expression of claudin-1 and ZO-1, and improves intestinal barrier function by regulating the composition of the intestinal microbiota

doi: 10.1186/1471-2474-7-52

These dual access points mean more patients qualify for affordable weight loss therapy

Researchers believe that hair loss during GLP-1 treatment is more related to underlying conditions than the drug itself