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In 2018, the U.S

Lancet 386 (10010), 22872323

The 2015 Institute of Medicine (IOM) report Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products notes that raising the minimum legal age of purchase of tobacco products would reduce youth smoking initiation, particularly among children ages 15 to 17, leading to substantial reductions in tobacco use, improve the health of Americans across lifespan, and save millions of lives

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rustica Nicotiana is part of the nightshade family ( Solanacceae ), so other nightshades may also contain nicotine Duboisia hopwoodii (pituri) from Australia is one example, leaves from which have been chewed as a stimulant by indigenous Australian communities for centuries