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Results revealed that treatment with the miR-34a-5p mimic at a dose of 1 nmol led to an approximately 4-fold increase in hepatic miR-34a-5p expression (Supplementary Figure S2A)

A significant positive correlation of 4-aminobiphenyl, a hepatic carcinogen in CS, with HCC risk has been shown in humans (Wang et al., 1998

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p53 mediates the transcription of genes encoding damaged DNA binding protein 2 ( DDB2/p48 ) and xeroderma pigmentosum group C ( XPC ) proteins, involved in the global genome NER that repairs dipyrimidine photoproducts [31]

As such, as previously mentioned, the generic effect of UVR will be addressed

Role of Nicotine in Cancer May damage DNA May contribute to tumor growth Prevents chemotherapy drugs from killing cancer cells Why do most cancers take so long to develop