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Smoking is a major global public health issue and the leading preventable cause of illness and death, being responsible for over eight million deaths annually, including 1.3 million non-smokers affected by second-hand smoke

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This results in: a significantly shorter time needed to find the correct fuse, a reduced likelihood of damaging the system by removing the wrong component, more predictable and organized electrical system operation

That is 5-10 times higher than the background mutation rate, Alexandrov says, noting that background rate depends on age, ethnicity and other factors

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