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138 Lung-specific transgenic expression of VEGF induced, next to angiogenesis, edema, inflammation, vascular and parenchymal remodeling, a marked Th2 sensitization towards a model allergen, OVA.This was mainly attributed to epithelial and Th2-cell-derived VEGF

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7 However, decreased CYP2A6 activity may influence smoking and carcinogen exposure in any smoker, and the relationship of nicotine metabolism and CYP2A6 genotype to the lung cancer risk of smokers of European descent was recently established in the Transdisciplinary Research in Cancer of the Lung consortium genome-wide association study data set

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