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To assess the effectiveness of smoking cessation interventions in smokers undergoing lung cancer screening, 10 RCTs (reported across 12 publications) were selected through a systematic search and screening process.281, 336, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453 Pooled analysis of nine studies revealed no statistically significant difference in smoking cessation rates at three months or longer between the intervention group and the control group that received minimal or usual care (RR, 1.56