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Fewer cigarettes mean less tar and other harmful substances entering the lungs, leading to better respiratory health and reduced coughing and shortness of breath

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As a sensitivity test, the one-step DerSimonian and Laird estimator provides a summary effect of 1.80 (0.842.76) which is not meaningfully different from the two-step result

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Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice