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"We don't have the long-term studies to show the effects of COPD [chronic obstructive pulmonary disease] or cancer, but our concerns are that it's very similar in the way that it took years for us to figure out that tobacco led to, with definite science, led to things like cancer and development of COPD," Rizzo added

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Specifically, we are using Infinium MethylationEPIC arrays and looking at promoter methylation changes and comparing the results with our RNA-Seq data