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In San Francisco, stores, bars, restaurants and other retail can obtain a tobacco sales permit

9, pages 465-479

Many farmers who farm tobacco dont make enough money to support their households and are incapable of sustaining losses

The nicotine contained in tobacco first stimulates and later depresses the central nervous system

That means genetically modified plants can not only directly impact pesticide use, by making themselves more resistant to pests, but also in second order fashion by helping to create insect pheromones to research environmentally safe alternatives to insecticides

[13] The packaging is also attractive to children